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RECENT ADDITIONS: Key Issues and Outcome Studies
Waitlist-controlled trial of cognitive behavior therapy for hoarding disorder. Steketee, G., Frost, R. O., Tolin, D. F., Rasmussen, J., & Brown, T. A.
Depression and Anxiety ,27(5), May 2010, 476-484.
Correspondence Address:
Steketee, Gail: Boston University School of Social Work, 264 Bay State Rd., Boston, MA, US, 02215-1409, steketee@bu.edu.
Abstract
This study investigated a multicomponent cognitive behavioral treatment (CBT) for hoarding based on a model proposed by Frost and colleagues and manualized in Steketee and Frost (2007). Method: Participants with clinically significant hoarding were recruited from the community and a university-based anxiety clinic. Of the 46 patients randomly assigned to CBT or waitlist (WL), 40 completed the 12-week assessment and 36 completed 26 sessions. Treatment included education and case formulation, motivational interviewing, skills training for organizing and problem solving, direct exposure to nonacquiring and discarding, and cognitive therapy. Measures included the Saving Inventory-Revised (self-report), Hoarding Rating Scale-Interview, and measures of clinical global improvement. Between group repeated measures analyses using general linear modeling examined the effect of CBT versus WL on hoarding symptoms and moodstate after 12 weeks. Within group analyses examined pre-post effects for all CBT participants combined after 26 sessions. Results: After 12 weeks, CBT participants benefited significantly more than WL patients on hoarding severity and mood with moderate effect sizes. After 26 sessions of CBT, participants showed significant reductions in hoarding symptoms with large effect sizes for most measures. At session 26, 71% of patients were considered improved on therapist clinical global improvement ratings and 81% of patients rated themselves improved; 41% of completers were clinically significantly improved. Conclusions: Multicomponent CBT was effective in treating hoarding. However, treatment refusal and compliance remain a concern, and further research with independent assessors is needed to establish treatment benefits and durability of gains. (PsycINFO Database Record (c) 2010 APA, all rights reserved).
RECENT ADDITIONS: Cognitive Mediation Research
Cognitive mediation of clinical improvement after intensive exposure therapy of agoraphobia and social phobia.
By Vögele, Claus; Ehlers, Anke; Meyer, Andrea H.; Frank, Monika; Hahlweg, Kurt; Margraf, Jürgen. Depression and Anxiety, Vol 27(3), Mar 2010, 294-301.
Key Finding: Background: The present study investigated cognitive mediation of clinical improvement in patients with agoraphobia (N = 427) or social phobia (N = 98) receiving high-density exposure therapy in a naturalistic clinical treatment setting. Methods: Patients were assessed before therapy, 6 weeks after the end of therapy, and 1 year thereafter, using a self-report assessment battery. Lower level mediation analyses provided support for the notion that cognitive changes partially mediate clinical improvement after exposure therapy. Results: Changes in cognitions relating to physical catastrophes mediated treatment outcome only for patients with agoraphobia, whereas changes in cognitions about loss of control mediated outcome for both agoraphobia and social phobia patients. Changes in relationship satisfaction did not mediate symptomatic improvement. Conclusions: The results extend previous findings by demonstrating mediation in an unselected clinical sample and by providing evidence for the specificity of mediation effects. They further support the importance of cognitive changes in cognitive-behavior therapy ((PsycINFO Database Record (c) 2010 APA, all rights reserved).
Long-term effects of cognitive behavior therapy on brain activation in spider phobia.
By Schienle, Anne; Schäfer, Axel; Stark, Rudolf; Vaitl, Dieter. Psychiatry Research: Neuroimaging, Vol 172(2), May 15, 2009, 99-102.
Key Finding: This functional magnetic resonance imaging study investigated long-term effects of cognitive behavior therapy (CBT) in individuals suffering from spider phobia. Ten female patients who had shown positive immediate CBT effects were invited to take part in a 6-month follow-up investigation. Here, the patients, along with eight non-phobic females, were presented with the same pictures depicting spiders, generally disgust-inducing, generally fear-inducing and neutral content, which they had viewed 6 months earlier. Patients' self-report and overt behavior indicated a positive long-term clinical improvement. Related hemodynamic changes included an increase in medial orbitofrontal cortex (OFC) activity. As the medial OFC is involved in emotion-related learning, especially in the representation of positive stimulus-outcome associations, we conclude that the medial OFC effect constitutes the neuronal basis of the lasting positive CBT outcome. Activity to disorder-irrelevant pictures decreased across the sessions in the lateral OFC and in the insula, which most likely reflects general habituation. (PsycINFO Database Record (c) 2010 APA, all rights reserved).
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